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Tocris Bioscience™ AGN 193109

High affinity pan-RAR antagonist

Overview
236.80 GBP valid until 2025-07-30
Use promo code "24078" to get your promotional price.

Additional Details:
Additional Details: Weight: 0.00970kg



Disclaimers: For Research Use Only

Product Code. 18776496

Quantity Price
1 £ 296.0 / 10mg
Estimated Shipment
18-06-2025
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Description and Specification

Specification

Product Type Antagonist
Target Proteins Retinoic Acid Receptor
CAS 171746-21-7
Molecular Formula C28H24O2
Formula Weight 392.49g/mol
Content And Storage Store at -20°C
For Use With (Application) Retinoic Acid Receptor Antagonists
Quantity 10 mg

AGN 193109 is a high affinity pan-retinoic acid receptor (RAR) antagonist (Kd values are 2, 2 and 3 nM at RARα, RARβ and RARγ, respectively). Exhibits no significant affinity for retinoic X receptors. AGN 193109 promotes the differentiation from mouse embryonic stem cells into paraxial mesoderm. AGN 193109 suppresses primary human cardiovascular smooth muscle cell calcification.

AGN 193109 synthesized to Ancillary Material Grade also available.

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