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Invitrogen™ Human TIMP2 ELISA Kit

ELISA

£594.0 - £2520.0

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Specification

Accession Number P16035
Assay Sensitivity 2 pg/mL
Assay Solid-phase sandwich ELISA
Conjugate HRP
Product Type ELISA
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Specification

Accession Number P16035
Assay Sensitivity 2 pg/mL
Assay Solid-phase sandwich ELISA
Conjugate HRP
Product Type ELISA
Protein Family Proteases, Peptidases & Inhibitors
Sample Type Plasma,Serum,Supernatant
Specificity This ELISA kit shows no cross-reactivity with any of the cytokines tested: Human IL-1 alpha, IL-1 beta, IL-2, IL-3, IL-4, IL-5, IL-7, IL- 8, IL-9, IL-10, IL-11, IL-12 p70, IL-12 p40, IL-13, IL-15, G-CSF, GM-CSF, IFN-gamma, MCP-1, MCP-2, MCP-3, MDC, MIP-1 alpha, MIP-1 beta, PDGF, SCF, TNF-alpha, TNF-beta, TPO, VEGF.
Target Species Human
For Use With (Application) ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 7077
Interassay CV <12%
Intraassay CV <10
Label or Dye HRP
Regulatory Status RUO
Research Discipline Other Research
Storage Requirements 2°C to 8°C
Target TIMP2
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

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Invitrogen™
EHTIMP2
 96 Tests £594.0
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EHTIMP2X5
 5 x 96 Tests £2520.0
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