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Trimethylacetyl chloride, 98+%

CAS: 3282-30-2 | C5H9ClO | 120.58 g/mol

£21.65 - £177.0

Chemical Identifiers

CAS 3282-30-2
Molecular Formula C5H9ClO
Molecular Weight (g/mol) 120.58
MDL Number MFCD00000709
InChI Key JVSFQJZRHXAUGT-UHFFFAOYSA-N
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
PubChem CID 62493
IUPAC Name 2,2-dimethylpropanoyl chloride
SMILES CC(C)(C)C(Cl)=O
View More Specs

Disclaimers: RUO – Research Use Only


Specification

Chemical Name or Material Trimethylacetyl chloride
CAS 3282-30-2
Melting Point -57°C
Density 0.985
Boiling Point 105°C to 106°C
Flash Point 8°C (46°F)
Odor Pungent
Molecular Formula C5H9ClO
Refractive Index 1.412
MDL Number MFCD00000709
Quantity 100 mL
UN Number UN2438
Beilstein 385668
Sensitivity Moisture sensitive
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Synonym pivaloyl chloride,trimethylacetyl chloride,propanoyl chloride, 2,2-dimethyl,pivalyl chloride,pivaloylchloride,2,2-dimethylpropionyl chloride,pivalic acid chloride,pivalolyl chloride,unii-jq82j0o21t,2,2-dimethylpropionylchloride
Solubility Information Miscible with acetonitrile.
InChI Key JVSFQJZRHXAUGT-UHFFFAOYSA-N
SMILES CC(C)(C)C(Cl)=O
IUPAC Name 2,2-dimethylpropanoyl chloride
Molecular Weight (g/mol) 120.58
PubChem CID 62493
Formula Weight 120.58
Percent Purity ≥98%

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.

Product Code Brand Quantity Price ??product.searchResults.label.quantityAvail??
Quantity
11680212


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A15051.AE
 100 mL £21.65
100mL
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11431960


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A15051.AP
 500 mL £53.65
500mL
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11441960


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A15051.0F
 2500 mL £177.0
2500mL
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Product Identifier
  • Trimethylacetyl chloride

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 2
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 1
  • Flammable liquid Category 2
  • Substances and mixtures corrosive to metals Category 1
  • Skin corrosion/irritation Category 1 B

Hazard Statement
  • H225- Highly flammable liquid and vapour.
  • H290- May be corrosive to metals.
  • H302- Harmful if swallowed.
  • H314- Causes severe skin burns and eye damage.
  • H318- Causes serious eye damage.
  • H330- Fatal if inhaled.

Precautionary Statement
  • P210- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280- Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331- IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353- IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310- Immediately call a POISON CENTER/doctor/.

Supplemental Information
  • MIXTURE LIST- Contains : Pivaloyl chloride